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Drive Chart
| Qtr | Team | Details | Start | Drive | Score |
| 1 | BUF | Rian Lindell 35 yard field goal is GOOD. Holder-Shawn Powell | BUF27 | 10 plays, 56 yards | 0 - 3 |
| 2 | BUF | Rian Lindell 40 yard field goal is GOOD. Holder-Shawn Powell | STL39 | 7 plays, 17 yards | 0 - 6 |
| 3 | STL | Steven Jackson Off Right Guard for 1 yard for a TOUCHDOWN | STL30 | 11 plays, 70 yards | 7 - 6 |
| 3 | BUF | Ryan Fitzpatrick Pass to Lee Smith for 2 yards for a TOUCHDOWN | BUF25 | 9 plays, 75 yards | 7 - 12 |
| 4 | STL | Sam Bradford Pass to Brandon Gibson for 13 yards for a TOUCHDOWN | STL16 | 15 plays, 84 yards | 15 - 12 |
| Scoring Summary | |||
| First Quarter | StL | Buf | |
 |
Rian Lindell 35 yd FG 2:14 Drive: 10 Plays, 56 Yards, 5:37 |
0 | 3 |
| Second Quarter | StL | Buf | |
|
Rian Lindell 40 yd FG 0:07 Drive: 7 Plays, 27 Yards, 1:08 |
0 | 6 |
| Third Quarter | StL | Buf | |
 |
Steven Jackson 1 yd run (Greg Zuerlein kick) 8:37 Drive: 11 Plays, 70 Yards, 6:23 |
7 | 6 |
|
Lee Smith 2 yd pass from Ryan Fitzpatrick (failed 2pt Pass from Rian Lindell) 3:26 Drive: 9 Plays, 75 Yards, 5:11 |
7 | 12 |
| Fourth Quarter | StL | Buf | |
|
Brandon Gibson 13 yd pass from Sam Bradford (Chris Givens 2pt Pass from Sam Bradford) 0:48 Drive: 14 Plays, 84 Yards, 4:07 |
15 | 12 |
| Team Stats | ||
| StL | Buf | |
| First Downs | 17 | 17 |
| Rushing | 5 | 3 |
| Passing | 11 | 13 |
| Penalty | 1 | 1 |
| 3rd Down Efficiency | 7-17, 41% | 3-12, 25% |
| 4th down efficiency | 1-1, 100% | 0-0, -% |
| Red-Zone Efficiency | 2-2, 100% | 1-3, 33% |
| Goal-To-Go Efficiency | 1-1, 100% | 0-0, -% |
| Total Net Yards | 285 | 281 |
| Total Plays | 67 | 58 |
| Yards/Play | 4.3 | 4.8 |
| Net Rushing Yards | 78 | 61 |
| Rushes | 27 | 20 |
| Yards/Carry | 2.9 | 3.1 |
| Rushing TDs | 1 | 0 |
| Net Passing Yards | 207 | 220 |
| Comp-Att-Int | 19-39-1 | 25-33-1 |
| Yards/Attempt | 5.2 | 5.8 |
| Passing TDs | 1 | 1 |
| Sack-Yds | 1-2 | 5-27 |
| Return Yards | 132 | 146 |
| Punt Returns-Yards | 2-23 | 4-44 |
| Punt Return TDs | 0 | 0 |
| Kick Returns-Yards | 4-88 | 3-79 |
| Kick Return TDs | 0 | 0 |
| Int Returns-Yards | 1-21 | 1-23 |
| Int Return TDs | 0 | 0 |
| Punts-Average | 8-37.8 | 7-39.1 |
| Penalties - Yards | 2-17 | 2-15 |
| Fumbles Lost | 2-0 | 2-1 |
| Own-Recover-Yards | 2-0 | 1-0 |
| Own-Recover TDs | 0 | 0 |
| Opp-Recover-Yards | 1-4 | 0-0 |
| Opp-Recover TDs | 0 | 0 |
| Field Goals | 0-0, -% | 2-2, 100% |
| Extra Points | 1-1, 100% | 0-0, -% |
| Two Point Conversions | 1-1, 100% | 0-1, 0% |
| Safeties | 0 | 0 |
| Time of Possession | 29:24 | 30:36 |
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